Flesh and Spirit

Scripture: John 3:6 (ESV) – “That which is born of the flesh is flesh, and that which is born of the Spirit is spirit.”

John Calvin, in his Commentary on the Gospel of John, underscores the distinction Jesus makes between two types of birth: physical and spiritual. “Flesh” refers to natural human birth, characterized by human frailty and the inability to achieve righteousness before God. In contrast, being “born of the Spirit” signifies the divine, transformative work of the Holy Spirit, which brings new life and enables entrance into the kingdom of God.

Calvin emphasizes that human nature, corrupted by sin, cannot produce the spiritual rebirth necessary for salvation. Efforts rooted in the flesh—our natural inclinations, works, and understanding—are inadequate to bring about spiritual renewal. Only the Spirit of God can regenerate the heart, giving rise to a new creation in Christ. This highlights the absolute dependence of humanity on God’s grace for salvation.

The statement, “That which is born of the Spirit is spirit,” signifies the radical transformation brought about by the Spirit’s work. Calvin reminds us that this spiritual rebirth is not a partial improvement of human nature but a complete renewal. The believer, born of the Spirit, is fundamentally changed, possessing a new heart, desires, and orientation toward God.

This verse calls us to acknowledge the limits of human effort in matters of salvation and to rely entirely on the Spirit for true spiritual life. It also challenges us to live according to the Spirit, reflecting the transformation that has occurred in our lives.

Reflection Questions:

  1. How does Jesus’ distinction between flesh and Spirit challenge your understanding of spiritual growth and transformation?
  2. Are there areas in your life where you are relying on your own strength (“the flesh”) rather than the Spirit?
  3. How can you daily embrace and live out the reality of being “born of the Spirit”?

Prayer:
Lord God, thank You for teaching us that true life comes only through the work of Your Spirit. Help us to recognize the limits of our own efforts and to rely fully on Your transformative power. Renew our hearts and lives through Your Spirit, enabling us to live as new creations in Christ. May we reflect the fruit of the Spirit in all we do and grow daily in our relationship with You. In Jesus’ name, Amen.


This devotional is based on John Calvin’s commentary on John 3:6, highlighting his insights on the necessity of the Spirit’s work for spiritual transformation.

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